Recombinant Keratin 6 anticorps (C-Term)

N° du produit ABIN7795792

Cet anticorps anti-Keratin 6 est un anticorps Lapin Monoclonal détectant Keratin 6 dans IHC, WB, ICC et IP. Adapté pour Humain.

Aperçu rapide pour Recombinant Keratin 6 anticorps (C-Term) (ABIN7795792)

Antigène: Keratin 6 (KRT6)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Keratin 6 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Clone: BLR357N

Détail du produit anti-Keratin 6 anticorps

Épitope: C-Term

Fonction: Rabbit anti-Cytokeratin 6 Recombinant Monoclonal Antibody [BLR357N]

Purification: Purified

Immunogène: between 514 and 564 (C-term)

Isotype: IgG

Information d'application

Indications d'application: IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.,IP,20 μL/mg lysate,WB,11,000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 250 μg/mL

Buffer: Phosphate Buffered Saline (PBS) with 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: 2 - 8 °C

Date de péremption: 12 months

Détails sur Keratin 6

Antigène: Keratin 6 (KRT6)

Autre désignation: Cytokeratin 6

Sujet: Cytokeratins 5 and 6 are type II cytokeratins and consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. In normal tissue, Cyokeratin 5 is specifically expressed in the basal layer of the epidermis with family member KRT14 while Cytokeratin 6 is expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. Cytokeratins 5 and 6 are often referred to together as "CK5/6", and are commonly expressed in various cancers, particularly those originating from epithelial tissues, and their presence is often used as a marker to identify squamous cell carcinomas or tumors with a basal cell-like phenotype [taken from NCBI Entrez Gene (Gene ID: < a href="https://www.ncbi.nlm.nih.gov/gene/3852" class="gene-values" target="_blank">3852 and < a href="https://www.ncbi.nlm.nih.gov/gene/3853" class="gene-values" target="_blank">3853)].

ID gène: 3853

UniProt: P02538